zum Inhalt springen

Research area A: Mitochondrial dynamics and quality control

The adaptation of mitochondrial function to changing physiological demands is of utmost importance to maintain cell homeostasis and survival. The functional plasticity of mitochondria is closely linked to their dynamic behaviour, which is in the centre of the work in research area A.

Projects focus on mechanisms that regulate mitochondrial dynamics, prevent the accumulation of mitochondrial damage and preserve cell homeostasis. The regulation of dynamin-like GTPases acting on the outer and inner membrane and the crosstalk with cellular surveillance mechanisms, cell signalling and metabolism is of central importance.