24Jun
mitoRTG Lecture by Prof. Matteo Bergami - 24 June 2026
Title: Mitochondria in Neuronal Function and Neurodegeneration | Date: Wednesday, 24.06.2026 at 12 pm | Venue: CECAD Lecture Hall, ground floor
News
Mitochondria are dynamic and plastic organelles that are integrated into a complex network of cellular signalling cascades. They respond to alterations in cellular physiology and they themselves signal to determine cell fate and function. These complex and bi-directional interactions of mitochondria with the cell have implications for their role in disease. The CRC 1218 will tackle the challenge of mitochondrial complexity using novel interdisciplinary and collaborative approaches.
Upcoming Events
29Jul
mitoRTG Lecture by Dr. Sebastian Willenborg - 29 July 2026
Title: tba | Date: Wednesday, 29.07.2026 at 12 pm | Venue: CECAD Lecture Hall, ground floor
29Jul
mitoRTG Lecture by Dr. Sebastian Willenborg
Title: tba
Latest Publications
MAY 2026| Cytosolic PRDX1 acts as an extramitochondrial sink to set mitochondrial H2O2 levels and enable resilience to chronic mitochondrial oxidative stress. Redox Biol. (2026). (Jan Riemer | project B02)
FEBRUARY 2026| Mitochondria contact lipid droplets through the mitochondrial import complex binding to lipid metabolism enzyme Ayr1. Nat Cell Biol (2026). (Thomas Becker | project B11)
JANUARY 2026| Mitochondrial contact site and cristae organizing system promotes modular assembly of cytochrome c oxidase. Cell Rep. (2026). (Thomas Becker | project B11)
NOVEMBER 2025| The Myo2 adaptor Ldm1 and its receptor Ldo16 mediate actin-dependent lipid droplet motility. Cell Rep. (2025). (Thomas Becker | project B11)
OCTOBER 2025 | Leucine inhibits degradation of outer mitochondrial membrane proteins to adapt mitochondrial respiration. Nat Cell Biol (2025). (Thorsten Hoppe|project B03)
SEPTEMBER 2025 | Ubiquitin precursor with C-terminal extension promotes proteostasis and longevity. Mol Cell (2025). (Mafalda Escobar-Henriques | project A03) and (Thorsten Hoppe|project B03)
AUGUST 2025 | 2-hydroxyglutarate mediates whitening of brown adipocytes coupled to nuclear softening upon mitochondrial dysfunction. Nat Metab. (2025). (Aleksandra Trifunovic | project B01)
APRIL 2025| The mitochondrial unfolded protein response: acting near and far. Biol Chem. (2025). (Thorsten Hoppe|project B03)
MARCH 2025| Unclogging of the TOM complex under import stress. Biol Chem. (2025). (Thomas Becker | project B11)
MARCH 2025 | Tissue-specific adaptations to cytochrome c oxidase deficiency shape physiological outcomes. BBA (2025). (Aleksandra Trifunovic | project B01)
FEBRUARY 2025 | Mitofusin 2 displays fusion-independent roles in proteostasis surveillance. Nat Commun. (2025). (Mafalda Escobar-Henriques | project A03)
FEBRUARY 2025| Mitochondrial heterogeneity: subpopulations with distinct metabolic activities. Sig Transduct Target Ther. (2025). (Thomas Becker | project B11)
JANUARY 2025| Mitochondrial protein import stress. Nat Cell Biol (2025). (Thomas Becker | project B11)
NOVEMBER 2024| Monitoring α-helical membrane protein insertion into the outer membrane of yeast cells. Methods Enzym. (2024). (Thomas Becker | project B11)
JULY 2024| Mitochondrial complexome and import network. Trends Cell Biol. (2024). (Thomas Becker | project B11)
FEBRUARY 2024 | Chronic endoplasmic reticulum stress in myotonic dystrophy type 2 promotes autoimmunity via mitochondrial DNA release. Nat Commun. (2024). (Aleksandra Trifunovic | project B01)
DECEMBER 2023 | Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes. Nature (2023). (Aleksandra Trifunovic | project B01)
OCTOBER 2023 | COX17 acetylation via MOF-KANSL complex promotes mitochondrial integrity and function. Nat Metab. (2023). (Mauro Corrado | B12, Thomas Becker | B11)
OCTOBER 2023 | cIAPs control RIPK1 kinase activity-dependent and -independent cell death and tissue inflammation. EMBO J. (2023). (Hamid Kashkar | project B06)
AUGUST 2023 | E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response. Molecular Cell (2023). (Mafalda Escobar-Henriques | project A03)
