SESSION 1:	MITOCHONDRIA IN ENERGY METABOLISM
14:00--14:15	WELCOME
CHAIR:	Ulrich Brandt, Radboud University Medical Center, Nijmegen, The Netherlands
14:15--14:45	Matthew HIRSCHEY, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC/USA "Regulation of energy metabolism by post-translational protein modifications"
14:45--15:15	Aleksandra FILIPOVSKA, University of Western Australia, Australia "Fidelity of mitochondrial translation: the good, the bad and the cardiomyopathy"
15:15--15:45	Jean-Claude MARTINOU, University of Geneva, Switzerland "Identification of mitochondrial RNA granules assembly factors and regulators using an image-based siRNA screen"
15:45--16:15	Discussions with coffee
16:15--16:45	Peter REHLING, University of Göttingen, Germany "Biogenesis of mitochondrial membrane protein complexes"
16:45--17:15	Eileen WHITE, State University of New Jersey, USA "Dual role of mitochondria in tumor initiation and progression"
17:15--17:45	Judy HIRST, MRC Mitochondrial Biology Unit, UK "The structure of mammalian respiratory complex I and what it can teach us about mitochondrial diseases"
17:45--18:15	Aleksandra TRIFUNOVIC, University of Cologne, Germany "Keeping complex I in shape"

SESSION 2:	THE DYNAMIC MITOCHONDRION: COMPONENTS, ARCHITECTURE AND CONTACTS
CHAIR:	Mafalda Escobar, CECAD Research Center/Institute for Genetics University of Cologne
09:15--10:00	mito-RTG Lecture: Heidi McBRIDE, McGill University, Canada "Iron delivery to mitochondria"
10:00--10:30	William PRINZ, National Institute of Diabetes and Digestive and Kidney Disease, USA "Link between lipid synthesis and transport to mitochondria"
10:30--11:00	David PAGLIARINI, University of Wisconsin-Madison, USA "Defining mitochondrial protein function through systems biochemistry"
11:00--11:30	Discussions with coffee
11:30--12:00	Werner KÜHLBRANDT, Max Planck Institute of Biophysics, Germany "CryoEM of ATP synthase"
12:00--12:30	Oliver DAUMKE, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany "Structural and functional studies on mitochondrial membrane remodeling machineries"
12:30--14:00	Lunch break

SESSION 3:	SIGNALLING TO AND FROM MITOCHONDRIA
CHAIR:	Thomas Langer, Max Planck Institute for Biology of Ageing, Cologne
14:00--14:30	Martin GRAEF, Max Planck Institute for Biology of Ageing, Cologne "Beyond mitophagy: multilayered interactions of autophagy machinery and mitochondria"
14:30--15:00	Mike MURPHY, MRC Mitochondrial Biology Unit, UK "Mitochondrial metabolism and redox signalling"
15:00--15:30	Agnieszka CHACINSKA, Centre of New Technologies, Poland "Guided tour of proteins into mitochondria"
15:30--16:00	Discussions with coffee
16:00--16:30	Fabiana PEROCCHI, Ludwig-Maximilians-University Munich, Germany "Systematic reconstruction of mitochondrial calcium signalling networks"
16:30--17:00	Erika PEARCE, Max Planck Institute for Immunobiology and Epigenetics, Germany "Polyamines modulate mitochondrial respiration through eIF5A hypusination"

SESSION 4:	MITOCHONDRIA IN PATHOPHYSIOLOGY AND DIFFERENTIATION
CHAIR:	Elena Rugarli, CECAD Research Center/Institute for Genetics University of Cologne
09:00--09:30	Richard YOULE, National Institutes of Health, USA "How PINK1- and Parkin-mediated mitophagy prevents neurodegeneration"
09:30--10:00	Hamid KASHKAR, University of Cologne, Germany "Mitochondrial control of endothelial function during development and disease"
10:00--10:30	Michael DUCHEN, University College London, UK "Linking mitochondrial dysfunction to neurodegeneration: Impaired mitochondrial bioenergetic capacity sensitises neurons to calcium overload"
10:30--11:00	Discussions with coffee
11:00--11:30	Thomas SCHWARZ, Harvard Medical School, USA "On the distribution of power: moving and removing mitochondria in neurons"
11:30--12:00	Mary HERBERT, Newcastle University, UK "Transmission of mtDNA disease: How to get from risk reduction to prevention?"
12:00	Closing address

The programme consists only of oral presentations given by the invited speakers; there will be no poster session.